Life Science Research Professional 2 (1 Year Fixed-Term), Stanford

Research Specialist (Life Science Research Professional 2)

We are seeking a highly skilled and motivated Research Specialist for a 1 year fixed-term to join our laboratory focused on understanding resilience and plasticity during mammalian embryogenesis. Our work combines in vivo lineage tracing, single-cell genomics, and genetic perturbation approaches to study how embryos recover from developmental perturbations.A central component of this role will be the generation and maintenance of transgenic mouse lines. We are looking for someone with deep technical expertise and hands-on experience across all stages of mouse transgenesis. Key Responsibilities Perform all aspects of mouse transgenesis, including: Superovulation and timed matingsEmbryo isolation (zygote and blastocyst stages) Microinjection or electroporation of embryos Blastocyst handling, culture, and manipulation Surgical transfer of embryos into pseudopregnant recipients Establish and expand transgenic founder lines Genotype and validate transgenic animals Maintain detailed experimental records and ensure high reproducibilityCollaborate closely with lab members on experimental design and execution Contribute to optimizing and developing new transgenic approaches What We Offer A collaborative and intellectually stimulating research environment Opportunities to contribute to cutting-edge studies in developmental biologyCompetitive salary and benefits package This position is offered as a one-year fixed-term appointment, with strong potential for extension based on performance and continued funding. Desired Qualifications: Bachelor's or Master's degree in Biology or a related field (PhD preferred but not required)Experience with CRISPR/Cas9 genome editing in embryos Familiarity with generating knock-in/knockout models Experience managing mouse colonies and transgenic workflows Background in developmental biology or genetics Must be comfortable working with mice Extensive hands-on experience in mouse transgenesisDemonstrated proficiency in: Superovulation and embryo collection Micromanipulation of embryos (injection and/or electroporation) Embryo culture and blastocyst handling Survival surgery for embryo transfer into pseudopregnant females Strong understanding of mouse reproductive biology and embryologyExcellent surgical skills and attention to detail Ability to work independently and troubleshoot complex protocols Education&Experience (Required): Bachelor's degree in related scientific field and two years of relevant work experience; or Master's degree in a related scientific field. Knowledge, Skills and Abilities (Required): Comprehensive understanding of scientific principles. General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications. Strong analytical skills and excellent judgment. Ability to maintain detailed records of experiments and outcomes. Ability to work under deadlines with general guidance is essential. Excellent organizational skills and demonstrated ability to accurately complete detailed work.Physical Requirements*: Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. Must have correctible vision to perform duties of the job. Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours. Ability to lift heavy objects weighing up to 50 pounds. Ability to work in a dusty, dirty, and odorous environment. Position may require repetitive motion. Add or subtract physical requirements based on the requirements of your specific job.Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job. Working Conditions: May require working in close proximity to blood borne pathogens. May require work in an environment where animals are used for teaching and research. Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator. May require extended or unusual work hours based on research requirements and business needs.