Scientist II, Massachusetts

Job Description:

Discovery Biotherapeutics and Genetic Medicine is seeking a highly motivated research scientist to join the Cell and Functional Biology group. In this role, you will be responsible for the execution of cell- and protein- based functional characterization assays for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The ideal candidate should have strong experience working with antibodies, significant experience in immunoassays (such as ELISAs) and familiarity with automation technologies is highly valued. The applicant should be able to analyze, document, and report data. The applicant should possess excellent communication skills and be comfortable presenting in group settings.

Responsibilities:

Conduct high throughput antibody screening and characterization to assess binding, functional and polyreactive attributes

Analyze and interpret results, placing data in proper scientific context through review of relevant literature and reporting these findings at team meetings.

Perform general laboratory research competently and independently, modifying and troubleshooting experimental design and instrumentation to suit the needs of research.

Support the expansion of high throughput screening platforms and assay design and the evaluation of Client technologies.

The ideal candidate is expected to work on multiple projects in a team environment.

Requirements:

Bachelor's Degree or equivalent education with typically 3-5 years of experience.

Masters with 2 years' experience .

Strong experience with binding assays (e.g. ELISA, flow cytometry).

Experience with automated liquid handling.

Experience with biologics, antibodies and mimetics.

Strong cell culture techniques.

Excellent oral and written communication skills.

Excellent organization skills and the ability to manage multiple projects simultaneously.

Team player with the ability to operate in a fast-paced multi-disciplinary environment.

Adapt to rapid changes in project priorities and timelines.

Competency with software programs, including MS Excel, PowerPoint, Word.

Experience with high throughput screening.

Proficiency with scientific software programs (e.g. GraphPad Prism, FlowJo).

Top Skills Required:

ELISA

FACS

Cell culture

Automated liquid handling

HTP screening